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Ghostface is trading small town life for big city streets in the first full length trailer for Scream VI.

Sisters Sam (Melissa Berrera) and Tara Carpenter (Jenna Ortega), and siblings Chad (Mason Gooding) and Mindy Meeks-Martin (Jasmin Savoy Brown) have tried to move on from the bloody events of Scream 5 by relocating to New York City. But a new killer has suited up as Ghostface, and in the trailer he or she is not shy about attacking them in the corner store or on a crowded subway car.

The trailer shows Gale Weathers (Courteney Cox) investigating and challenging the latest killer, and popular Scream 4 character Kirby Reed (Hayden Panettiere) makes her return to the franchise. The footage also teases a Ghostface museum/shrine filled with the killer’s costumes, Billy Loomis’ shirt, the outfit Tatum Riley was wearing when she died, a sketch of Kirby, and much more.

Scream VI is directed by Matt Bettinelli-Olpin and Tyler Gillett, the pair who co-directed the fifth installment. Voice actor Roger Jackson is back for his sixth round of voicing Ghostface. New cast members include Devyn Nekoda, Josh Segarra, Tony Revolori, and Dermot Mulroney.

It will be in theaters on March 10, 2023.